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Copperartemisinin nanoprodrugs (CuART NPs) catalyze ROS generation, disrupting mitochondrial membrane potential and triggering apoptosis/ferroptosis (164)

The MGBA immune links described earlier (Th17 cells, etc.) are pertinent too PD patients have been found to have increased Th17 cells in circulation, and recent research implicates gut bacteria in shaping this PD-specific immune profile [161]

[DOI] [PubMed] [Google Scholar] Guo C, Liang F, Shah Masood W, Yan X (2014)

Kamerbeek NM, van Zwieten R, de Boer M, Morren G, Vuil H, Bannink N, Lincke C, Dolman KM, Becker K, Schirmer RH, et al

consultant: AbbVie, Acadia, Alkermes, Axsome, Biogen, Boehringer Ingelheim, Bristol Myers Squibb, Corium, Intra-Cellular, Johnson & Johnson, Lundbeck, MedinCell, Moderna, Neurocrine, Noven, Otsuka, Sage, Sumitomo, Supernus, Teva