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[298] S-adenosylmethionine (SAMe), a naturally occurring sulfur-bearing compound, plays a regulatory role in various biochemical processes vital to eye health

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To investigate whether the M9a haplogroup confers a biochemical advantage under hypoxic conditions, we first selected the plain M7/8 haplogroups, which are sister branches of the M9a haplogroup, as controls to minimize the introduction of additional mutations