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For instance, numerous studies have demonstrated that exercise performed in the afternoon or early evening, when core body temperature and muscle strength peak, tends to elicit greater improvements in cardiorespiratory fitness, body composition, and insulin sensitivity compared to morning workouts

[Accessed on 24th June 2022] 3

Recent studies indicate that periodontitis, as a prevalent chronic oral infectious disease, not only causes local microbial dysbiosis and inflammatory responses but may also influence central nervous system function through the oral-gut-brain axis, thereby contributing to the pathogenesis and progression of neurodegenerative diseases such as Alzheimers disease, Parkinsons disease, and multiple sclerosis, as well as neuropsychiatric disorders like depression

3 times per week for 7-10 week Result:Prevented the significant decline in cardiac function of Dox-treated p53 / mice (study week 7 versus 10) along with rescuing the decreased mitochondrial respiration and tissue ATP depletion caused by Doxorubicin (Dox)

PMID: 17707063