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The main role of this pathway is to nitrogen balance in the whole body and requires five urea cycle enzymes, carbamoyl phosphate synthase I (CPS1), ornithine transcarbamylase (OCT), argininosuccinate synthase (ASS), argininosuccinate lyase (ASAL), and arginase-1 (ARG1)

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GLP-1 agonists were initially developed to manage type 2 diabetes, and some studies have shown evidence that they might have positive effects on cardiovascular health