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Schrepf A, Bradley CS, O'Donnell M et al: Toll-like receptor 4 and comorbid pain in interstitial cystitis/bladder pain syndrome: A multidisciplinary approach to the study of chronic pelvic pain research network study

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Besides activation of the complement system, another activation was seen with cytomegalovirus (CMV) and Epstein-Barr virus (EBV) specific antibodies, with the former correlating with extent of symptoms