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Description

The characteristic hypermethylation within promoter regions of colorectal cancer tumor suppressor genes indicates that the epigenome likely plays a key role in mediating non-genetic sequence modifications driving malignant phenotype (182)

Aging 34 , 15641580 (2013)

This intricate pathway is crucial for maintaining cellular balance, and dysregulation can contribute to a myriad of diseases, including cancer, fibrosis, and immune disorders