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The enzymes involved in these processes are dedicated oxidases (e.g., DsbAB system in bacteria, Ero1 and Erv1 in eukaryotic cells) and isomerases (e.g., DsbC/D system in bacteria, PDI in eukaryotic cells) [133]

During this process, nuclear factor erythroid 2-related factor 2 (Nrf2), an essential transcription factor located in the cytoplasm responsible for activating the antioxidant system, translocates into the nucleus to promote the expression of antioxidant enzymes such as heme oxygenase-1 (HO-1), thereby mitigating oxidative stress [61,62,63]

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Research also suggests it helps with the integration of bone grafts, which could be beneficial for certain surgical procedures

The assay mixture contained 2 mL of solution (800 mol) and 2.5 ml of phosphate buffer in a 10 mL flat bottom flask