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Reportedly, glucose deprivation boosts up the reactive oxygen species and causes the death of cancer cells through inhibiting glycolysis and the pentose phosphate pathway [12], and lactic acid is known to promote NADPH production and maintains redox balance [13]

Respiratory chain dysfunction and oxidative stress correlate with severity of primary CoQ10 deficiency

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J Physiol Sci 66(2):113125 Li HT, Jiao M, Chen J, Liang Y (2010) Roles of zinc and copper in modulating the oxidative refolding of bovine copper, zinc superoxide dismutase