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Indeed, a pilot study on young patients with ALL suffering from chemo-induced liver toxicity found that treatment with milk thistle led to a "trend towards significant reductions in liver toxicity."24 The researchers state that future studies are needed to zero in on the ideal dosage and duration of treatment, but their findings suggest that milk thistle may be a promising intervention for acute liver injury secondary to chemo

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When FOXO4 protein binds with p53, it does not appear to allow p53 to bind with DNA, thereby preventing apoptosis and cell death

[DOI] [PMC free article] [PubMed] [Google Scholar] 15.Pribis JP, Zhai Y, Hastings PJ & Rosenberg SM Stress-induced mutagenesis, gambler cells, and stealth targeting antibiotic-induced evolution