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Description

J Clin Invest 2009;119:709

When a therapeutic dose of acetaminophen is taken, this quinone intermediate is conjugated with glutathione and excreted in the urine

Figures were created in biorender.com

When a trigger reaches them, an enzyme called tyrosinase ramps up production and the result is a darker patch: sun spots, post-inflammatory marks after a spot or a scratch, or melasma