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Researchers demonstrated that Co-Cr alloys upregulate downstream HO-1 and activate the Nrf2/ARE signaling pathway, which results in cytotoxicity and inflammation

Similarly, gelatin coatings (5.40%) with 18% plasticizer delayed tomato ripening as shown by slower maturation and lower redness (a*) in coated tomatoes during 20 days of storage, demonstrating its protective effect in extending tomato shelf life (Fig

Furthermore, ESM1 upregulates inflammatory factors such as TNF- and IL-8, both of which can activate NF-B (58,70,71)

This includes vitamin B12