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It is found in virtually every cell of the body and plays a critical role in protein synthesis, synthesis and repair of DNA, enzyme function, transport, and cell maturation

Cura, A

J Clin Endocrinol Metab (2006) 91(8):317180

The models above seem related to motivational deficits relevant to depression (reverted by bupropion) and secondary NS related to AP (reverted by antiparkinsonism drugs)

Further definition of this relationship could serve as a crucial push towards alleviation of a plethora of diseases related to oxidative stress, especially since mitochondrial ALDH2 is known to be a plausible therapeutic target