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Prefrontal cortex infusion of beta-hydroxybutyrate, an endogenous NLRP3 inflammasome inhibitor, produces antidepressant-like effects in a rodent model of depression

Data were extracted into a standardized table capturing Study design, Sample size and population, Intervention or exposure (e.g., antioxidant agent, mitochondrial marker), Outcomes (e.g., pain, fatigue, oxidative markers), Key findings relevant to the PICO questions above

Examples include insulin, endorphins, and oxytocin

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Detoxification : Glutathione aids in the detoxification of harmful compounds, including heavy metals and environmental toxins