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vascular endothelial growth factor (VEGF) and angiopoietin-1, leading to the induction of genes involved in angiogenesis and thus represent therapeutic targets for the inhibition of tumor angiogenesis [122]

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Fluoroquinolone antibiotics can form zwitterion coordinated with Cu 2+ through the pyridone carbonyl oxygen and carboxylate oxygen, or anionic bidentate ligand coordinated through the pyridone carbonyl oxygen and carboxylate oxygen (Nedeljkovi et al