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Thus, the gene coding for gamma-glutamylcysteine synthetase (g-ECS) (the rate limiting enzyme in the synthesis of GSH) must be a critical downstream target gene of H2O2 triggered signal transduction

To further demonstrate activation of the TSS pathway by DMF, we investigated the metabolism of serine for de novo cysteine biosynthesis by 13 C 3 -serine tracing (Fig

Records of the hypoglycemic episode, including circumstances, symptoms, and response to treatment, is essential

Importantly, in the male adrenal, we find that HHEX protects the inner zF from androgen-induced lipophagy (lipid depletion) at puberty

J Appl Toxicol 2017;37:117481