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Ischemia is lack of oxygen and reperfusion is reintroducing oxygen

10.1371/journal.pone.0048811 25 HorstN

Other simple coumarins include magnolioside, (S)-peucedanol-7-O--d-glucopyranoside, (S)-peucedanol-3-O--d-glucopyranoside and isoapiosylskimmin

The free aldehyde in the open-chain form of the alkenal adduct can react with a second lysine, histidine, or cysteine and then can act as a heterobifunctional cross-linking reagent