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Description

Achieving standardization across the entire workflow from sample collection and preservation to analytical determination constitutes a necessary prerequisite for translating metabolomic research findings into clinical diagnostic and therapeutic decision-making tools

10.1073/pnas.0911187107 172 Von MuhlinenN.AkutsuM.RavenhillB

Therefore, disruption of endocannabinoid signaling between neurons and astrocyteswhich naturally occurs during agingcauses a deleterious transition in astrocytes that perpetuates cytokine-mediated damage