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C3 is a critical component in hypertension pathogenesis due to its maintenance effect on undifferentiated mesenchymal stem cells (MSCs), and maternal and placental C3a levels are upregulated in women with preeclampsia, indicating aberrant CS activation (479)

Whole blood was layered on to ficoll histopaque in a 1:1 ratio and centrifuged at 25C for 30 minutes at 1800 RPM with the slow brake to prevent disturbance of the gradient

Thus, decreasing oxidative stress could attenuate cognitive deficits induced by hypoxia

Behavioral studies were also performed to evaluate the improvement of cognitive performance and memory function induced by all treatments (180)

Aithal GP, Ramsay L, Daly AK, Sonchit N, Leathart JBS, Alexander G, Kenna JG, Caldwell J, Day CP