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Abstract Background Chondrocyte homeostasis is vital for maintaining the extracellular matrix (ECM) and overall cartilage health

NIP IgG1 WT and REW were administered i.v

One important caveat: wound serum from chronic wounds (such as diabetic ulcers) contains enzymes that break down GHK-Cu, which may limit topical efficacy on infected or chronic wounds

Until a more thorough understanding is achieved through rigorous clinical trials and research, any application of FOXO4-DRI must be navigated with utmost caution and under strict medical oversight

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