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Biscetti et al

This is accompanied by endothelial dysfunction, which leads to pathogenic changes in microvascular tone, permeability, and leukocyte adhesion 13

Kozic, D

doi: 10.3390/ijms160818185 197

978 An open-label randomized noninferiority study (NCT02041299) on SCD patients showed that DFP and DFO were equally effective in reducing liver iron concentrations, with acceptable efficacy and safety, consistent with results seen in transfusion-dependent thalassemia patients