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synthetically generated CpG containing hexamers &/or oligos containing CpG containing hexamers poly A, C, G, T, etc

Notably, high-dose Rb resulted in stronger enrichment of glutamate and GSH pathways, implying impaired antioxidant defense

Useful effects of cannabinoids in animals have been mentioned e.g., for disorders of the cardiovascular system, pain treatment, disorders of the respiratory system or metabolic disorders

So in ALS, rather than driving pathology, the baseline microbiome might be trying to counteract it, and losing key microbes removes that brake on microglial activation