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Results: Within total subjects, free carnitine, acylcarnitine, and total carnitine levels were significantly increased without statistical change in serum ammonia, valproic acid levels, and acylcarnitine/free carnitine ratio, while a part of Brief Psychotic Rating Scale scores was decreased

Nikulin et al., 2006

Injectable Strategies and Limitations While topical application is preferred for patient compliance, invasive routes may be necessary for therapeutic targets deep within the lens

A review on advanced CRISPR-based genome-editing tools: base editing and prime editing

4).8 Adolescent patients In the ALLEGRO-2b/3 trial, 15% of the population consisted of hard-to-treat adolescents with SALT 50% (severe AA), a mean disease duration of 6.5 years, and 40% with AT or AU.8 Although limited by small sample size, the results were consistent with those in the overall study population