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Description

M., Sorochynska O

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Inflammaging aggravates stroke pathology

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Ferroptosis is a form of regulatory cell death, as increased iron accumulation in the brain leads to lipid peroxidation, reactive oxygen species (ROS) production, mitochondrial dysfunction and neuroinflammatory responses, resulting in cellular and neuronal damage

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304 Compared with control mice, p53-deficient mice develop atherosclerosis more quickly in the presence of comparable serum cholesterol levels

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We find that oxidation on a conserved cysteine in the kinase activation loop of SEK-1 is essential for pathogen defense in C

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