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Cell Biol Int 1998

*Correspondence: Fabrizio Schifano, [email protected] This article was submitted to Addictive Disorders, a section of the journal Frontiers in Psychiatry Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

developed a novel DON prodrug, HDON, which can selectively activate nitroreductase in hypoxic tumor environments without affecting oxygen-rich normal tissues, showing significant tumor inhibition in the H22 mouse liver cancer model (Zheng et al., 2024)

Metabolism of dietary L-carnitine by intestinal microbiota produced trimethylamine-N-oxide, a proatherogenic species, which accelerated atherosclerosis (30)

Epub 2023 Mar 28