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The enthesis organ concept and its relevance to the spondyloarthropathies

These gene products are responsible for a wide range of antioxidant, anti-inflammatory, cytoprotective, and detoxification functions and include catalase, superoxide dismutase (SOD)-3, heme oxygenase-1, glutathione-S-transferases, NAD(P)H-quinone oxidoreductase (NQO1), glutathione peroxidase, and glucuronosyltransferase-1a6 (UGT-1a6) [11]

In such compounds, nitrogen occupies the center of a tetrahedron, with its four sp 3 hybrid orbitals directed toward the vertices: three are occupied by substituents, while the fourth contains a nonbonding electron pair

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