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Oxidative deamination of methylamine by semicarbazide-sensitive amine oxidase leads to cytotoxic damage in endothelial cells

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2006;290:L93145

In addition to potential ergogenic impact, these authors also reported that caffeine significantly improved various indicators of mood state [438, 440], lowered ratings of perceived exertion and decreased perception of muscle pain [439, 441] when acute doses of caffeine (5 mg/kg) were provided before maximal resistance exercise

This leads to irreparable oxidative damage to bacterial cell membranes and other functional biomolecules such as DNA, enzymes, and fatty acids, thereby exerting cytotoxic effects on both bacteria and tumor cells