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Symptoms of B12 deficiency closely mimic hypothyroid symptoms, including fatigue, brain fog, hair loss, and depression, which means your B12 issue may be mistaken for undertreated thyroid disease

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Calculation of the electrostatic surface potential shows that the external cleft of the H-site is hydrophobic, with a positively charged surface accommodating the COOH group of the CGL ligand (holoenzyme structure subunit A), beyond which the surface loses charge

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Current management strategies focus on premature delivery due to the lack of effective treatments to halt its progression