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In recent years, natural polyphenols have shown great potential in combating cisplatin ototoxicity due to their powerful antioxidant, anti-inflammatory and anti-apoptotic properties.A variety of polyphenolic compounds, such as resveratrol, curcumin, quercetin, etc., can effectively attenuate the damage of cisplatin on Corti organs, spiral ganglion neurons and vascular striatum by scavenging free radicals, inhibiting the release of inflammatory factors, and regulating the expression of apoptosis-related proteins

MOG autoantibodies trigger a tightly-controlled FcR and BTK-driven microglia proliferative response

A prospective study evaluating apremilast in psoriasis patients reported sustained PASI75 responses in more than 60% of patients after 40 weeks of therapy (Vujic et al

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Trends Cell Biol 30(10):777791