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TGF- synergizes with ML264 to block IL-1-induced matrix degradation mediated by Krppel-like factor 5 in the nucleus pulposus

112, tables, detailed experimental procedures, synthetic methods, characterization data and additional experimental details

ALS can occur sporadically or in familial forms, with mutations in genes like superoxide-dismutase1 (SOD1) and TDP-43 being common causes that result in nerve cell degeneration and death (Jeon et al., 2019