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7 Future research directions Despite remarkable advances in understanding the reproductive toxicity of environmental endocrine disruptors, fundamental knowledge gaps continue to impede comprehensive risk assessment and effective intervention development

On the other hand, the most likely cellular targets for the occurrence of ferroptosis through iron supplementation may be the intestinal cells themselves and the intestinal microbiota, since, in humans, the intestinal absorption of iron is regulated by means of hepcidin [4]

AMPK phosphorylates NRF2 at the Ser550 residue located in the canonical NES sequence, facilitating NRF2 nuclear accumulation, probably by inhibiting nuclear export [212], and this effect is enhanced by GSK-3 inhibition [213]

Subjects infer the value of the relative reflectance ( y 1 ) and the 3D shape ( y 2 ) based on these observed cues

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