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After surgery, D-dimer increases, peaking at about one week and then decreasing by 5-10% daily

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(It is not indicated for the treatment of primary hemochromatosis, since phlebotomy is the method of choice for removing excess iron in this disorder.) Contraindications: Patients with severe renal disease or anuria, since the drug and the iron chelate are excreted primarily by the kidney Pharmacokinetics: Given parentally (i.m., s.c