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Resistant hypertension (assuming adherence checked and confirmed) Non-adherent patients (considering the extreme pill dysutility - bordering on pill hatred - in some patients) Renal denervation potentially provides a smoother BP lowering, unlike the vagaries of troughs and peaks, heightened by the occasional missed dose, with pharmacotherapy - does this justify using renal denervation more widely

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Targeted disruption of the mouse 3-phosphoglycerate dehydrogenase gene causes severe neurodevelopmental defects and results in embryonic lethality

Seek immediate medical attention if severe reactions occur

For instance, marine mussels leverage metal coordination bonds to construct hierarchical material structures, achieving exceptional strength, elasticity, and toughness (Waite et al., 2005)