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Resveratrol protects H9c2 cells against hypoxia-induced apoptosis through miR-30d-5p/SIRT1/NF-kappaB axis

In a landmark human trial comparing topical GHK-Cu to vitamin C and retinoic acid (tretinoin), GHK-Cu produced measurable collagen increases in 70% of study volunteers outperforming both comparator treatments (Abdulghani et al., 1998)

International Journal of Molecular Sciences, 22 (19), 10376.

GHK-Cu and Angiogenesis Research Laboratory and in vivo studies found that GHK-Cu stimulates collagen synthesis, angiogenesis, and the modulated expression of glycosaminoglycans, proteoglycans, and metalloproteinases with in vivo animal models reinforcing these findings and reporting accelerated wound-healing rates and favourable wound-contracture properties

Liver X Receptors (LXRs) and Farnesoid X Receptor (FXR) are two nuclear receptors that act as intracellular sensors for sterols and bile acids, respectively