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58 Up-regulation of AKT and MAPK signaling pathways were reported to promote angiogenesis and enhance wound healing in the male diabetic mice skin wound models

They tell cells to repair, regenerate, release growth hormone, modulate inflammation, or support metabolic balance

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With fewer sebaceous glands and lower baseline collagen turnover, expect a 30% to 40% improvement in wrinkle depth for mild-to-moderate photodamage over 12 to 16 weeks