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Participants saw rapid initial loss through weeks 4 to 12, peak velocity between weeks 12 and 24 (roughly 1.8 pounds per week), gradual slowing between weeks 24 and 36, and a plateau or near-plateau by weeks 44 to 48

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Compounds used in scientific research should never be used outside of a laboratory

3,17 Pharmacologic treatment of PCOS should be individualized, symptom oriented, and combined with continued lifestyle counseling

While everyone should have proper diet and nutrition there are sections of the population that have a greater need to monitor their B12 levels