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Metabolism of excessive intracellular glucose can occur by several processes such as aldose reductase, mitochondrial oxidative phosphorylation, activation of NAD(P)H oxidases, and the alteration of the NADPH/NADP ratios

de Havenon A, Khatri P , Prabhakaran S, Yeatts S, Peterson C, Sacchetti D, Alexander M, Cutting S, Mac Grory B, Furie K, Liebeskind D, Yaghi S

2006, 7: 8-doi:10.1186/1471-2156-7-8 Serajee FJ, Nabi R, Zhong H, Huq AHMM: Polymorphisms in xenobiotic metabolism genes and autism

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After two weeks, the rats' weights were recorded before administering any treatment and beginning the experiment