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In skeletal muscle, IGF-1 LR3 activates satellite cells, promoting their proliferation and differentiation into mature muscle fibersa process termed hyperplasia (increase in cell number) distinct from hypertrophy (increase in cell size)

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The 2-Week Rule A helpful guideline many clinicians use is this: If a side effect appears for the first time after two weeks of stable treatment, or worsens significantly after the initial adjustment period, it deserves provider evaluation

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A provider reviews your history and prescribes the protocol that fits your goals