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10.1007/978-3-030-85686-1_4 Adv Exp Med Biol

Multiple research investigations have shown that nitric oxide (NO) may encourage and prevent the growth and spread of tumours

Given that this study examined the short-term effects of N-acetylcysteine, it may be possible to gain a deeper understanding of its effects through long-term studies on this substance

The abnormal expression of these proteins provides evidence that exosomes from HACE patients may contribute to disruptions in neurodevelopment, thereby affecting cognitive function

Another preclinical study using presymptomatic and symptomatic SOD1 G93A transgenic mice revealed an association between the accumulation of ceramides and cholesterol esters in the spinal cords of ALS patients and OS, thus highlighting the pivotal role of OS in inducing an alteration in the metabolism of sphingolipids metabolism which mediates MN death in ALS [112]