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The common treatment-associated adverse effects reported were manageable, including thrombocytopenia, anemia, alopecia, dysgeusia, neutropenia, lymphopenia, leukopenia, decreased appetite, and pyrexia

Epidemiological data and findings from mouse and human cell models indicate that particulate matter with an aerodynamic diameter smaller than 2.5 m (PM2.5) promotes lung cancer by stimulating the growth of lung cells with pre-existing carcinogenic mutations

Several mental disorders come under NPDs, such as anxiety, depression, autism spectrum disorder (ASD), attention deficit hyperactivity disorder (ADHD) and others like schizophrenia, bipolar disorder, mania, Parkinsons disease, Tourettes syndrome, delirium, dementia, vascular cognitive impairment and apathy

Nrf2 tends to promote the transcription of genes by heterodimerizing with Maf proteins or other homologs to a cis-acting DNA transcriptional regulator, specifically the antioxidant response element (ARE) (Zhu et al., 2016)