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doi:10.1007/978-94-007-5787-5_1

Further research confirms that ACSL4 suppression in early ischemic stages is time-dependent and likely driven by increased HIF-1, which binds to the ACSL4 promoter and suppresses its expression (137)

Indeed, a low concentration of 200 mg/day orally is capable of reducing IL-6 levels, which are inversely correlated with NKA release [73]

doi: 10.1007/s00125-011-2431-y 60 HubberELRackhamCLJonesPM