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ADs are becoming more prevalent in developed countries of the western world, with environmental factors, specifically dietary components, thought to be major contributing factors (Parks et al

Vero cells were grown in DMEM (Gibco 11965-092) with glucose (4.5 g/L) supplemented with 2% fetal bovine serum (FBS, Corning 35-010-CV)

At 24 h, the upregulation of HMOX1 and GADD45B remained significant in both cell types, but DNAJB1 regulation declined and was no longer significant in HepG2 ATP7B-KO cells

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IPC can induce prolonged HIF stabilization by ROS-related PHD inactivation [152]