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10.1016/j.jplph.2018.11.003 J Plant Physiol

Statistical Analysis and Graphing Software All statistical tests are t -tests with multiple comparisons corrected using false discovery rate (FDR) cutoff set to 1%

Short answer: raising circulating Lcarnitine is fast, but changing the carnitine content inside muscle fibers is slow and requires chronic dosing plus insulinmediated uptake

Treatment factors, such as cumulative dose, the duration of the chemotherapy treatment and concomitant administration of other medications such as triazole or imidazole have been associated with higher frequency and severity of CIPN following chemotherapy treatment (Table 5)

These enzymes and substrates can be explored as therapeutic targets for cancer