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Description

ChaC2 may be implicated in numerous vital physiological functions, including DNA replication and repair, cell cycle regulation, RNA and damaged DNA binding, oocyte meiosis and maturation (50)

412 Notably, the DESTINY-Breast series of studies has demonstrated significant benefits for patients with brain metastases, leading to T-DXd replacing TDM-1 and TKIs as the standard second-line treatment for advanced HER2+ breast cancer

Thus, controlling ferroptosis, preventing excessive cell death, and developing drugs that selectively kill tumor cells without disrupting the immune microenvironment are key challenges requiring further research

JAMA Psychiatry 79:571

Biochem Biophys Res Commun 339:12551261 Joost HG, Thorens B (2001) The extended GLUT-family of sugar/polyol transport facilitators: nomenclature, sequence characteristics, and potential function of its novel members (review)