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and the 2022 Monitoring Program

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Possible reasons include the Washington State University patent holders not finding a pharmaceutical company willing to invest in development, the cancer biology concern with c-Met activation making development companies cautious, the preclinical effect sizes in rats not justifying the expense and risk of human trials, or other factors specific to drug development economics

In rare cases, they might cause mild digestive issues like upset stomach or diarrhoea

This approach requires the most precise syringe work, which is why a lower concentration vial (5 mg/mL or 10 mg/mL) paired with a 0.3 mL syringe produces the best accuracy for microdosing