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On the other hand, while experimental approaches provide valuable insights into the biological effects of nutraceuticals, in silico molecular docking serves as a powerful computational tool to predict and elucidate the binding interactions between these compounds and their molecular targets (119)

Under certain physiological conditions first described in pregnancy (119, 120), specific proteases cleave IGFBP-3 into several proteolytic fragments of which each may retain immunoactivity and thus give rise to signals in an immunometric assay (121)

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