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Whether AOD-9604 at research doses causes clinically meaningful receptor downregulation in humans is unknown

Some GPs may incorrectly believe that only patients with a definite diagnosis of PA, those with a positive intrinsic factor antibody test, require treatment for life so seem to be using this as their treatment exclusion criteria

Mrowicka, J

In human studies, acute anorectic effect of OXM was demonstrated by intravenously infused OXM (139)

Insult to Induce Nerve Cell Damage To induce cellular damage (referred to as insult), we used 200 M hydrogen peroxide (H 2 O 2 ) for 6 h, as oxidative stress is one of the dominant mechanisms in the pathophysiology of PN