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DOI:10.1248/bpb.30.2007 [ Links ] 17

None of the animals were sacrificed for this study

Celastrol reduces RSL-3-induced oxidative stress and lipid peroxidation in HK-2 cells To further confirm the protective effects of celastrol against ferroptosis, we examined its impact on RSL-3-induced ferroptosis in HK-2 cells

However, these cell-specific effects do not occur in isolation

Gastric cancer Gastric cancer is among the top causes of cancer-related mortality worldwide, and its development is strongly associated with the gastric microbiota