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Gastrointestinal symptoms such as loss of appetite, constipation, or diarrhoea may also occur, though these are non-specific and can have many causes

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Given the high disease burden of NASH and limited therapeutic options currently available, the FDA has proposed an accelerated pathway for drug approval

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The most recent clinical study assessing LDN in patients with inflammatory bowel disease involved 19 Ulcerative colitis patients and 28 patients affected by Crohns disease