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Hum Reprod 2009;24:254-269

Peeking inside the Black Box: NMR Metabolomics for Optimizing Cell-Free Protein Synthesis

The discovered new types of inhibitors included DL-3(5-benzazolyl) alanines and alpha-methyldopa analogs 389 , aryl pyrazoles 390 , heterocyclic hybrids based on pyrazole and thiazolidinone scaffolds 391 , 3,5-diaryl-4,5-dihydro-1H 392 and 3,5-diaryl pyrazole derivatives 393 , pyrazolo[4,3-e][1,2,4]triazine sulfonamides and sildenafil 394396 , 1,3-oxazine-tetrazole 397 , indole-spliced thiadiazole 398 , benzimidazole-1,2,3-triazole hybrids 399 , 1,2,3-triazole-linked coumarinopyrazole conjugates 400 , isoxazolone derivatives 401 5(4H)-oxazolone derivative 402 , imidazolium ionic liquids 403 , thiazolyl resorcinols 404 have demonstrated the inhibitory effect on tyrosinase