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Presently, the maximum permissible AFs concentration in animal feeds is 5 g/kg based on EU limits (137)

Our group previously reported that oral GSH administration (500 mg/d) resulted in lightening of skin color, when given for 4 weeks

Similarly, pregnant or breastfeeding individuals should avoid use given unknown effects on fetal development

In the case of HD, a Phase I/II trial (NCT04120493) is testing the safety and efficacy of AAV5-miRNA, designed to silence the mutant huntingtin gene and slow disease progression

Dewson G, Kluck RM (2009) Mechanisms by which Bak and Bax permeabilise mitochondria during apoptosis